概述

  • 产品名称Anti-KLHL17抗体
    参阅全部 KLHL17 一抗
  • 描述
    兔多克隆抗体to KLHL17
  • 经测试应用适用于: ICC/IF, IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: AGAWESVAPM NIRRSTHDLV AMDGWLYAVG GNDGSSSLNS IEKYNPRTNK WVAASCMFTR RSSVGVAVLE LLNFPPPSSP TLSVS, corresponding to amino acids 554-638 of Human KLHL17.

  • 阳性对照
    • Human testis tissue; RT 4, U 51 MG and Human plasma lysates.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab122164 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

靶标

  • 功能Substrate-recognition component of some cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(KLHL17) mediates the ubiquitination and subsequenct degradation of GLUR6. May play a role in the actin-based neuronal function.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 BACK (BTB/Kelch associated) domain.
    Contains 1 BTB (POZ) domain.
    Contains 6 Kelch repeats.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Postsynaptic density.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Actinfilin antibody
    • AL022703 antibody
    • BC058738 antibody
    • kelch like 17 antibody
    • kelch like family member 17 antibody
    • kelch like protein 17 antibody
    • Kelch-like protein 17 antibody
    • KLH17_HUMAN antibody
    • Klhl17 antibody
    • RP11-54O7.6 antibody
    see all

Anti-KLHL17 antibody 图像

  • Immunofluorescent staining of Human cell line A-431 shows positivity in nucleus but not nucleoli. Recommended concentration of ab122164 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122164 at 1/100 dilution staining KLHL17 in Paraffin-embedded Human testis tissue by Immunohistochemistry.
  • All lanes : Anti-KLHL17 antibody (ab122164) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique

Anti-KLHL17 antibody (ab122164)参考文献

ab122164 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab122164.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"