概述

  • 产品名称Anti-KLF8抗体
    参阅全部 KLF8 一抗
  • 描述
    山羊多克隆抗体to KLF8
  • 经测试应用适用于: WBmore details
  • 种属反应性

    预测可用于: Human
  • 免疫原

    Synthetic peptide:

    VDMDKLINNLEVQ

    , corresponding to N terminal amino acids 2-14 of Human KLF8.

  • 阳性对照
    • Human Kidney lysate.
  • 常规说明Principal Names – KLF8; Kruppel-like factor 8; BKLF3; DXS741; ZNF741; zinc finger protein 741. Official Gene Symbol - KLF8. GenBank Accession Number – NP_009181. LocusLink ID - 11279 (human)

性能

应用

Our Abpromise guarantee covers the use of ab2747 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明Western Blot: Approx 50kDa band seen in Human Kidney lysate.
    Predicted molecular weight: 40 kDa.
    Recommended for use at 1.0-3.0µg/ml.
  • 靶标

    • 功能Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK).
    • 组织特异性Ubiquitous.
    • 序列相似性Belongs to the Sp1 C2H2-type zinc-finger protein family.
      Contains 3 C2H2-type zinc fingers.
    • 翻译后修饰Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G(1) phase. Has no effect on subcellular location.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Basic krueppel-like factor 3 antibody
      • BKLF3 antibody
      • DXS741 antibody
      • KLF8 antibody
      • KLF8_HUMAN antibody
      • Krueppel-like factor 8 antibody
      • Kruppel like factor 8 antibody
      • MGC138314 antibody
      • Zinc finger protein 741 antibody
      • ZNF741 antibody
      see all

    Anti-KLF8 antibody 图像

    Anti-KLF8 antibody (ab2747)参考文献

    ab2747 has not yet been referenced specifically in any publications.

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