概述

  • 产品名称Anti-Kir2.2抗体
    参阅全部 Kir2.2 一抗
  • 描述
    兔多克隆抗体to Kir2.2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 360-409 (KDLVENKFLL PSANSFCYEN ELAFLSRDEE DEADGDQDGR SRDGLSPQAR) of Human Kir2.2 (NP_066292).

  • 阳性对照
    • Human fetal brain lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
  • 序列相似性Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ATP sensitive inward rectifier potassium channel 12 antibody
    • ATP-sensitive inward rectifier potassium channel 12 antibody
    • hIRK antibody
    • Human high conductance inward rectifier potassium channel alpha antibody
    • Inward rectifier K antibody
    • Inward rectifier K(+) channel Kir2.2 antibody
    • Inward rectifier K(+) channel Kir2.2v antibody
    • inwardly rectifying subfamily J member 12 antibody
    • IRK-2 antibody
    • IRK12_HUMAN antibody
    • IRK2 antibody
    • KCNJ12 antibody
    • kcnj12x antibody
    • KCNJN1 antibody
    • Kir2.2v antibody
    • Potassium channel antibody
    • Potassium channel inwardly rectifying subfamily J member 12 antibody
    • Potassium inwardly rectifying channel subfamily J member 12 antibody
    • Potassium inwardly rectifying channel,subfamily J inhibitor 1 antibody
    see all

Anti-Kir2.2 antibody 图像

  • Anti-Kir2.2 antibody (ab84972) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal brain lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 49 kDa
    Observed band size : 49 kDa
    Gel concentration: 12%


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Heart Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Liver Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Lung Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Muscle Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Pancreas Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Stomach Lysate

Anti-Kir2.2 antibody (ab84972)参考文献

ab84972 has not yet been referenced specifically in any publications.

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