Anti-KIF5B抗体[KN-02] (ab11882)

概述

  • 产品名称Anti-KIF5B抗体[KN-02]
    参阅全部 KIF5B 一抗
  • 描述
    小鼠单克隆抗体[KN-02] to KIF5B
  • 特异性The antibody reacts with heavy chain of conventional kinesin associated with vesicles and with lower affinity with denaturated molecule. The antibody does not react with kinesin bound to taxol-stabilized microtubules.
  • 经测试应用适用于: ICCmore details
  • 种属反应性
    与反应: Mouse, Rat, Human, Pig
  • 免疫原

    Enriched fraction of porcine brain kinesin.

性能

应用

Our Abpromise guarantee covers the use of ab11882 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC Use at an assay dependent dilution.

靶标

  • 功能Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
  • 序列相似性Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
    Contains 1 kinesin motor domain.
  • 结构域Composed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.
  • 细胞定位Cytoplasm, cytoskeleton. Uniformly distributed between soma and neurites in hippocampal neurons.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Conventional kinesin heavy chain antibody
    • KIF 5B antibody
    • KIF5B antibody
    • Kinesin 1 antibody
    • kinesin 1 (110-120kD) antibody
    • Kinesin 1 heavy chain antibody
    • Kinesin family member 5B antibody
    • Kinesin heavy chain antibody
    • kinesin, heavy chain, ubiquitous antibody
    • Kinesin-1 heavy chain antibody
    • Kinesin1 antibody
    • KINH antibody
    • KINH_HUMAN antibody
    • KNS 1 antibody
    • KNS antibody
    • KNS1 antibody
    • Ubiquitous kinesin heavy chain antibody
    • UKHC antibody
    see all

Anti-KIF5B antibody [KN-02] 图像

  • Immunofluorescence staining of vesicles (red) in RBL-2H3 rat basophilic leukemia cell line using anti-KIF5B (ab11882). Nuclei were stained with DAPI (blue).

Anti-KIF5B antibody [KN-02] (ab11882)参考文献

ab11882 has not yet been referenced specifically in any publications.

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