概述

  • 产品名称Anti-KIF4A抗体
    参阅全部 KIF4A 一抗
  • 描述
    兔多克隆抗体to KIF4A
  • 经测试应用适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Elephant
  • 免疫原

    Synthetic peptide from a region between residue 1 and 50 of human KIF4A (NP_036442.3)

  • 阳性对照
    • Whole cell lysate from Hela cells.

性能

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应用

Our Abpromise guarantee covers the use of ab72337 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-5 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.
    • 组织特异性Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone marrow. Lower levels are found in heart, testis, kidney, colon and lung.
    • 序列相似性Belongs to the kinesin-like protein family. Chromokinesin subfamily.
      Contains 1 kinesin-motor domain.
    • 细胞定位Nucleus matrix. Cytoplasm > cytoskeleton > spindle. Midbody. Chromosome. Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Chromokinesin antibody
      • Chromokinesin-A antibody
      • Chromosome associated kinesin KIF4A antibody
      • Chromosome-associated kinesin KIF4A antibody
      • FLJ12530 antibody
      • FLJ12655 antibody
      • FLJ14204 antibody
      • FLJ20631 antibody
      • HSA271784 antibody
      • KIF4 antibody
      • KIF4 G1 antibody
      • KIF4A antibody
      • KIF4A_HUMAN antibody
      • KIF4G1 antibody
      • Kinesin family member 4A antibody
      see all

    Anti-KIF4A antibody 图像

    • Immunoprecipitation/ Western Blot of KIF4A.
      Lane 1: ab72337 at 3µg/mg whole cell lysate.
      Lane 2: Control IgG.
      Another antibody to KIF4A was used at 1µg/ml for WB.
      Whole cell lysate from Hela cells at 1mg for IP, 20% of IP loaded.
      Chemiluminescence with an exposure time of 10 seconds.

    Anti-KIF4A antibody (ab72337)参考文献

    ab72337 has not yet been referenced specifically in any publications.

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