概述

  • 产品名称Anti-KIF3A抗体[K2.4]
    参阅全部 KIF3A 一抗
  • 描述
    小鼠单克隆抗体[K2.4] to KIF3A
  • 特异性ab24626 appears to react with epitopes on the 85 subunit (KIF3A) of kinesin II lying outside the conserved motor domain.
  • 经测试应用适用于: Blocking, ICC/IF, WBmore details
  • 种属反应性
    与反应: Rat, Xenopus laevis, Sea Urchin
    预测可用于: all Mammals
  • 免疫原

    Full length native protein (purified)- kinesin II purified from unfertilized sea urchin egg cytosol.

  • 常规说明


    The antibody blocks ciliogenesis in urchin eggs.

性能

应用

Our Abpromise guarantee covers the use of ab24626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Blocking Use at an assay dependent dilution. It blocks ciliogenesis in urchin eggs.
ICC/IF Use at an assay dependent dilution.
WB 1/1000. Predicted molecular weight: 85-95 kDa.

靶标

  • 功能Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.
  • 序列相似性Belongs to the kinesin-like protein family. Kinesin II subfamily.
    Contains 1 kinesin-motor domain.
  • 细胞定位Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIF 3 antibody
    • KIF 3A antibody
    • KIF3 antibody
    • Kif3a antibody
    • KIF3A_HUMAN antibody
    • Kifl antibody
    • Kinesin family member 3A antibody
    • Kinesin family protein 3 antibody
    • Kinesin family protein 3A antibody
    • Kinesin like protein KIF 3A antibody
    • Kinesin like protein KIF3A antibody
    • Kinesin-like protein KIF3A antibody
    • Kns3 antibody
    • Microtubule plus end directed kinesin motor 3A antibody
    • Microtubule plus end-directed kinesin motor 3A antibody
    see all

Anti-KIF3A antibody [K2.4] 图像

  • Immunofluorescence analysis of rat hippocampal neurons, staining KIF3A with ab24626 at 1/500 dilution.

    Neurons were fixed in paraformaldehyde at 4°C for 20 minutes before incubation with the primary antibody. An AlexaFluor®-conjugated anti-mouse IgG was used as the secondary antibody (1/1000).

Anti-KIF3A antibody [K2.4] (ab24626)参考文献

This product has been referenced in:
  • Schwamborn JC  et al. The interaction of mPar3 with the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. J Biol Chem 282:35259-68 (2007). WB, IF ; Rat . Read more (PubMed: 17906294) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab24626.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"