概述

  • 产品名称Anti-KIF14抗体
    参阅全部 KIF14 一抗
  • 描述
    兔多克隆抗体to KIF14
  • 经测试应用适用于: IHC-P, ICCmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 1600 and the C terminus (amino acid 1648) of Human KIF14 (NP_055690.1).

  • 阳性对照
    • Formaldehyde fixed asynchronous HeLa cells.

性能

应用

Our Abpromise guarantee covers the use of ab92429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
ICC
  • 应用说明ICC/IF: Use at an assay dependent dilution.
    IHC-P (formaldehyde fixed): 1/100 - 1/500.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays an essential role in cytokinesis.
    • 序列相似性Belongs to the kinesin-like protein family.
      Contains 1 FHA domain.
      Contains 1 kinesin-motor domain.
    • 发展阶段Up-regulated in cells progressing through G2/M phase.
    • 细胞定位Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > spindle. Nuclear localization observed during interphase in PubMed:16431929 or triggered by entry into mitosis in PubMed:16648480. Cytoplasmic in interphase (PubMed:16648480) and metaphase cells (PubMed:16431929). From prophase to metaphase, accumulates at the developing spindle poles and their associated microtubules. During anaphase, accumulates at the spindle midzone. Localization to the central spindle and midbody during anaphase is dependent upon PRC1 and CIT presence. In cells ready to undergo abscission, concentrates at the contractile ring.
    • Information by UniProt
    • 数据库链接
    • 别名
      • KIAA0042 antibody
      • KIF 14 antibody
      • KIF14 antibody
      • KIF14_HUMAN antibody
      • Kinesin Family Member 14 antibody
      • Kinesin like protein KIF14 antibody
      • Kinesin-like protein KIF14 antibody
      • MGC142302 antibody
      see all

    Anti-KIF14 antibody 图像

    • Formaldehyde fixed asynchronous HeLa cells detected with ab92429 at a 1/100 dilution.
      Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed, used at a dilution of 1/100.

    Anti-KIF14 antibody (ab92429)参考文献

    ab92429 has not yet been referenced specifically in any publications.

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