概述

  • 产品名称Anti-KHDRBS3抗体
    参阅全部 KHDRBS3 一抗
  • 描述
    小鼠多克隆抗体to KHDRBS3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Full length human KHDRBS3 protein (NP_006549).

  • 阳性对照
    • Rat brain tissue lysate. KHDRBS3 transfected 293T lysate.

性能

应用

Our Abpromise guarantee covers the use of ab68515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).

靶标

  • 功能RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression.
  • 组织特异性Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis.
  • 序列相似性Belongs to the KHDRBS family.
    Contains 1 KH domain.
  • 结构域The proline-rich site binds the SH3 domain of the p85 subunit of PI3-kinase.
  • 翻译后修饰Phosphorylated on tyrosine residues. Isoform 1 C-terminal region is tyrosine-rich, but isoform 2 lacking this C-terminal region is also tyrosine-phosphorylated.
  • 细胞定位Nucleus. Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Etle antibody
    • etoile antibody
    • KH domain containing RNA binding signal transduction associated 3 antibody
    • KH domain containing RNA binding signal transduction associated protein 3 antibody
    • KH domain-containing antibody
    • KHDR3_HUMAN antibody
    • Khdrbs3 antibody
    • RNA binding protein T Star antibody
    • RNA-binding antibody
    • RNA-binding protein T-Star antibody
    • SALP antibody
    • Sam68 like mammalian protein 2 antibody
    • Sam68 like phosphotyrosine protein antibody
    • Sam68 like phosphotyrosine protein T STAR antibody
    • Sam68-like mammalian protein 2 antibody
    • Sam68-like phosphotyrosine protein antibody
    • signal transduction-associated protein 3 antibody
    • SLM 2 antibody
    • SLM-2 antibody
    • SLM2 antibody
    • T STAR antibody
    • TSTAR antibody
    see all

Anti-KHDRBS3 antibody 图像

  • Anti-KHDRBS3 antibody (ab68515) at 1/500 dilution + rat brain tissue lysate at 25 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 39 kDa
    Observed band size : 39 kDa
  • All lanes : Anti-KHDRBS3 antibody (ab68515) at 1/500 dilution

    Lane 1 : KHDRBS3 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 39 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

Anti-KHDRBS3 antibody (ab68515)参考文献

ab68515 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab68515.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"