概述

  • 产品名称Anti-KHDRBS2抗体
    参阅全部 KHDRBS2 一抗
  • 描述
    小鼠多克隆抗体to KHDRBS2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KHDRBS2 (NP_689901, 1 a.a. ~ 349 a.a) full-length human protein.

  • 阳性对照
    • KHDRBS2 transfected 293T lysate.

性能

应用

Our Abpromise guarantee covers the use of ab72690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 65 kDa (predicted molecular weight: 39 kDa).

靶标

  • 功能RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.
  • 组织特异性Highly expressed in brain, lung, kidney and small intestine. Weakly expressed in placenta, liver, spleen, thymus, ovary and colon.
  • 序列相似性Belongs to the KHDRBS family.
    Contains 1 KH domain.
  • 翻译后修饰Methylated.
    Tyrosine phosphorylated by FYN, PTK6 and SRC. Tyrosine phosphorylated by SRC during mitosis.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KH domain containing, RNA binding, signal transduction associated protein 2 antibody
    • 6330586C16Rik antibody
    • bA535F17.1 antibody
    • FLJ38664 antibody
    • hSLM 1 antibody
    • hSLM-1 antibody
    • KH domain containing, RNA binding, signal transduction associated 2 antibody
    • KH domain-containing antibody
    • KHDR2_HUMAN antibody
    • khdrbs2 antibody
    • MGC26664 antibody
    • RNA-binding antibody
    • Sam68 like mammalian protein 1 antibody
    • Sam68-like mammalian protein 1 antibody
    • signal transduction-associated protein 2 antibody
    • SLM 1 antibody
    • SLM-1 antibody
    • SLM1 antibody
    see all

Anti-KHDRBS2 antibody 图像

  • All lanes : Anti-KHDRBS2 antibody (ab72690) at 1/500 dilution

    Lane 1 : KHDRBS2 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 39 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)

Anti-KHDRBS2 antibody (ab72690)参考文献

ab72690 has not yet been referenced specifically in any publications.

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