概述

  • 产品名称Ketotifen fumarate
  • 描述
    Selective, H1 antagonist
  • 生物学描述Selective, non-competitive H1 antagonist. Inhibits phosphodiesterases and blocks Ca2+ channels.
  • 纯度> 99%

性能

  • 化学名称4,9-Dihydro-4-(1-methylpiperidin-4-ylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate
  • 分子量425.50
  • 化学结构Chemical Structure
  • 分子式C19H19NOS.C4H4O4
  • CAS编号34580-14-8
  • 存放说明Store at Room Temperature. The product can be stored for up to 12 months.
  • 溶解度概述Soluble in DMSO to 100 mM
  • 处理

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 来源

    Synthetic

  • 研究领域

    Ketotifen fumarate (ab120782)参考文献

    This product has been referenced in:
    • Monument MJ  et al. The mast cell stabilizer ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia: a study of a rabbit model of posttraumatic joint contractures. J Bone Joint Surg Am 92:1468-77 (2010). Read more (PubMed: 20516323) »
    • Sánchez-Patán F  et al. Mast cell inhibition by ketotifen reduces splanchnic inflammatory response in a portal hypertension model in rats. Exp Toxicol Pathol 60:347-55 (2008). Read more (PubMed: 18514499) »
    • Yamada Y  et al. Effect of ketotifen on the production of reactive oxygen species from human eosinophils primed by eotaxin. Pharmacology 69:138-41 (2003). Read more (PubMed: 14512700) »
    • Greenwood C The pharmacology of ketotifen. Chest 82:45S-48S (1982). Read more (PubMed: 6123414) »

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