Anti-KDM4B / JMJD2B抗体(ab91549)

概述

  • 产品名称Anti-KDM4B / JMJD2B抗体
    参阅全部 KDM4B / JMJD2B 一抗
  • 描述
    兔多克隆抗体to KDM4B / JMJD2B
  • 特异性ab91549 is specific for JMJD2B and will not recognize the other JMJD proteins.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 16 amino acid synthetic peptide from near the center of Human KDM4B/ JMJD2B (GenBank AAI36612).

  • 阳性对照
    • A20 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab91549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 2 µg/ml. Predicted molecular weight: 122 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
    • 序列相似性Belongs to the JHDM3 histone demethylase family.
      Contains 1 JmjC domain.
      Contains 1 JmjN domain.
      Contains 2 PHD-type zinc fingers.
      Contains 2 Tudor domains.
    • 结构域The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • JHDM3B antibody
      • JmjC domain-containing histone demethylation protein 3B antibody
      • JMJD2B antibody
      • Jumonji domain containing protein 2B antibody
      • Jumonji domain-containing protein 2B antibody
      • Kdm4b antibody
      • KDM4B_HUMAN antibody
      • KIAA0876 antibody
      • Lysine-specific demethylase 4B antibody
      see all

    Anti-KDM4B / JMJD2B antibody 图像

    • Lane 1 : Anti-KDM4B / JMJD2B antibody (ab91549) at 1 µg/ml
      Lane 2 : Anti-KDM4B / JMJD2B antibody (ab91549) at 2 µg/ml

      Lane 1 : A20 cell lysate
      Lane 2 : A20 cell lysate

      Lysates/proteins at 15 µg per lane.


      Predicted band size : 122 kDa

    Anti-KDM4B / JMJD2B antibody (ab91549)参考文献

    ab91549 has not yet been referenced specifically in any publications.

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    Unfortunately for this antibody we have data for WB and ELISA only and I am sure these applications does not involve fixing. The no data however does not mean that antibody is not suitable, it might be suitable how...

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    Thank you for contacting us.

    In regards to the homology observed between the sequence provided and the immunogen used to raise the antibodies mentioned, the highest percentage corresponds to ab91549, which shares 75% of the sequence.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"