Anti-KDEL Receptor抗体[2E7] (ab96720)

概述

  • 产品名称Anti-KDEL Receptor抗体[2E7]
    参阅全部 KDEL Receptor 一抗
  • 描述
    小鼠单克隆抗体[2E7] to KDEL Receptor
  • 经测试应用适用于: IHC-P, WB, ICC/IFmore details
  • 种属反应性
    与反应: Drosophila melanogaster, Plants, Wheat, Other
  • 免疫原

    synthetic peptide corresponding to the C-terminus of Saccharomyces cerevisiae KDEL receptor.

  • 阳性对照
    • Saccharomyces cerevisiae lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号2E7
  • 同种型IgG2b
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab96720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
WB 1/1000 - 1/2000. Predicted molecular weight: 78 kDa.
ICC/IF 1/50 - 1/100.

靶标

  • 相关性Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.
  • 细胞定位Endoplasmic reticulum
  • 别名
    • ER lumen protein retaining receptor 1 antibody
    • ERD 2 antibody
    • ERD2 antibody
    • ERD2.1 antibody
    • ERD21 antibody
    • HDEL antibody
    • KDEL (Lys Asp Glu Leu) endoplasmic reticulum protein retention receptor 1 antibody
    • KDEL (Lys-Asp-Glu-Leu) 72 kD endoplasmic reticulum protein retention receptor 1 antibody
    • KDEL endoplasmic reticulum protein retention receptor 1 antibody
    • KDEL R1 antibody
    • KDEL receptor 1 antibody
    • KDELR 1 antibody
    • KDELR1 antibody
    • PM 23 antibody
    • PM23 antibody
    • Putative MAPK activating protein PM23 antibody
    see all

Anti-KDEL Receptor antibody [2E7] 图像

  • ab96720 at 1/20,000 dilution staining KDEL Receptor in a Human kidney tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Secondary antibody was biotinylated Goat anti-mouse. Picture at 400X magnification.

Anti-KDEL Receptor antibody [2E7] (ab96720)参考文献

ab96720 has not yet been referenced specifically in any publications.

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