Anti-KDEL抗体[10C3] (Phycoerythrin) (ab115636)

概述

  • 产品名称Anti-KDEL抗体[10C3] (Phycoerythrin)
    参阅全部 KDEL 一抗
  • 描述
    小鼠单克隆抗体[10C3] to KDEL (Phycoerythrin)
  • 偶联物Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特异性ab115636 cross reacts with proteins containing the KDEL sequence.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性

    预测可用于: Bird, Plants, all Mammals
  • 免疫原

    Synthetic peptide:

    SEKDEL

    , corresponding to amino acids 649-654 of Rat KDEL.

  • 阳性对照
    • Jurkat cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号10C3
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/100.

靶标

  • 相关性The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
  • 细胞定位Endoplasmic reticulum
  • 别名
    • KDEL antibody
    • Lys Asp Glu Leu antibody

Anti-KDEL antibody [10C3] (Phycoerythrin) 图像

  • ab115636 at 10µg/ml staining KDEL in 106 Jurkat cells by Flow cytometry (shown in red).
    Grey: unstained;Yellow: isotype control.

Anti-KDEL antibody [10C3] (Phycoerythrin) (ab115636)参考文献

ab115636 has not yet been referenced specifically in any publications.

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