概述

  • 产品名称Anti-KCTD12抗体
    参阅全部 KCTD12 一抗
  • 描述
    兔多克隆抗体to KCTD12
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Guinea pig, Chimpanzee, Rhesus monkey, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 125-175 of Human KCTD12 (NP_612453.1).

  • 阳性对照
    • 293T, HeLa and Jurkat whole cell lysates

性能

应用

Our Abpromise guarantee covers the use of ab124260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000 - 1/10000.
IP Use at 2-10 µg/mg of lysate.

靶标

  • 功能Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
  • 组织特异性Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C13orf2 antibody
    • BTB/POZ domain-containing protein KCTD12 antibody
    • KCD12_HUMAN antibody
    • KCTD12 antibody
    • KIAA1778 antibody
    • PFET1 antibody
    • Pfetin antibody
    • potassium channel tetramerisation domain containing 12 USA antibody
    • Predominantly fetal expressed T1 domain antibody
    see all

Anti-KCTD12 antibody 图像

  • All lanes : Anti-KCTD12 antibody (ab124260) at 0.1 µg/ml

    Lane 1 : 293T whole cell lysate at 50 µg
    Lane 2 : 293T whole cell lysate at 15 µg
    Lane 3 : Jurkat whole cell lysate at 50 µg
    Lane 4 : HeLa whole cell lysate at 50 µg

    Developed using the ECL technique

    Exposure time : 30 seconds
  • Lane 1: ab124260 at 1 µg/ml staining KCTD12 in 293T whole cell lysate immunoprecipitated using ab124260 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Lane 2: Control IgG.
    Detection: Chemiluminescence with exposure time of 10 seconds.

Anti-KCTD12 antibody (ab124260)参考文献

ab124260 has not yet been referenced specifically in any publications.

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