概述

  • 产品名称Anti-KCNT1抗体
    参阅全部 KCNT1 一抗
  • 描述
    兔多克隆抗体to KCNT1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from the C terminal region of Human KCNT1.

  • 阳性对照
    • Human brain tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: without Mg2+ and Ca2+
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111051 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Outwardly rectifying potassium channel subunit that may co-assemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro).
  • 组织特异性Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.
  • 序列相似性Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
    Contains 1 RCK N-terminal domain.
  • 翻译后修饰Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA100C15.2 antibody
    • EIEE14 antibody
    • ENFL5 antibody
    • KCa4.1 antibody
    • KCNT1 antibody
    • KCNT1_HUMAN antibody
    • Potassium channel subfamily T member 1 antibody
    • Potassium channel, sodium activated subfamily T, member 1 antibody
    • Potassium channel, subfamily T, member 1 antibody
    • Sequence like a calcium-activated K+ channel antibody
    • SLACK antibody
    • Slo2.2 antibody
    see all

Anti-KCNT1 antibody 图像

  • ab111051 1/50 dilution staining KCNT1 in paraffin-embedded Human brain tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-KCNT1 antibody (ab111051)参考文献

ab111051 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111051.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"