Anti-KCNN2/SK2抗体(ab111939)
Key features and details
- Goat polyclonal to KCNN2/SK2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-KCNN2/SK2抗体
参阅全部 KCNN2/SK2 一抗 -
描述
山羊多克隆抗体to KCNN2/SK2 -
宿主
Goat -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Dog -
免疫原
Synthetic peptide corresponding to Human KCNN2/SK2 aa 500-600 (internal sequence). (NP_067627.2)
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阳性对照
- WB: Human liver lysate. IHC-P: Human kidney and thyroid tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111939于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 64 kDa.
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IHC-P |
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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WB
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 64 kDa. |
IHC-P
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. -
组织特异性
Widely expressed. -
序列相似性
Belongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 404177 Cow
- Entrez Gene: 474640 Dog
- Entrez Gene: 3781 Human
- Entrez Gene: 140492 Mouse
- Entrez Gene: 54262 Rat
- Omim: 605879 Human
- SwissProt: Q6PJI0 Human
- SwissProt: Q9H2S1 Human
see all -
别名
- Apamin sensitive small conductance Ca2+ activated potassium antibody
- Apamin sensitive small conductance Ca2+ activated potassium channel antibody
- hSK2 antibody
see all
图片
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Anti-KCNN2/SK2 antibody (ab111939) at 0.3 µg/ml + Human liver lysate in RIPA buffer at 35 µg
Predicted band size: 64 kDa
Primary incubation was 1 hour. Detected by chemiluminescence. -
ab111939, at 3.75 µg/ml, staining KCNN2/SK2 in formalin fixed, paraffin embedded human kidney by Immunohistochemistry.
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ab111939, at 3.75 µg/ml, staining KCNN2/SK2 in formalin fixed, paraffin embedded human thyroid by Immunohistochemistry.
数据表及文件
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Datasheet download
文献 (1)
ab111939 被引用在 1 文献中.
- Zhang XD et al. Coupling of SK channels, L-type Ca2+ channels, and ryanodine receptors in cardiomyocytes. Sci Rep 8:4670 (2018). PubMed: 29549309