Anti-KCNN1抗体(ab66624)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to KCNN1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Horse, Cow, Cat, Dog, Pig
  • 免疫原

    A region within synthetic peptide: QAQKLRSVKI EQGKLNDQAN TLTDLAKTQT VMYDLVSELH AQHEELEARL, corresponding to C terminal amino acids 433-482 of Human KCNN1

  • 阳性对照
    • Jurkat cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab66624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 32, 60 kDa (predicted molecular weight: 60 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
  • 序列相似性
    Belongs to the potassium channel KCNN family. KCa2.1/KCNN1 subfamily.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • hSK1 antibody
    • KCa2.1 antibody
    • KCNN 1 antibody
    • Kcnn1 antibody
    • KCNN1_HUMAN antibody
    • Potassium intermediate/small conductance calcium activated channel subfamily N member 1 antibody
    • SK antibody
    • SK1 antibody
    • SKCa 1 antibody
    • SKCa1 antibody
    • Small conductance calcium activated potassium channel protein 1 antibody
    • Small conductance calcium-activated potassium channel protein 1 antibody
    see all

Anti-KCNN1 antibody 图像

  • Anti-KCNN1 antibody (ab66624) at 1.25 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 60 kDa
    Observed band size : 32,60 kDa (why is the actual band size different from the predicted?)

实验方案

Anti-KCNN1 antibody (ab66624)参考文献

ab66624 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry.
In order to predict crossreactivity of this antibody with the mouse sequence, I have asked the laboratory to provide a sequence alignment with the mouse sequence. Unfortunately the sequence of the immunogen is only to 7...

Read More

Thank you for your message and your interest in ab66624.
In order to be able to provide you with a testing discount offer, I would need to know in what application or species you would like to test the ab66624. Please explain shortly how you would...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册