概述

  • 产品名称
    Anti-KCNK5抗体
  • 描述
    兔多克隆抗体to KCNK5
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Horse, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 236 - 285 (AWLSLFVNWK VSMFVEVHKA KKRRRRRKES ESSPHSRKAL MAGSTAS) of Mouse KCNK5 (NP_067517).

  • 阳性对照
    • Mouse liver lysate

性能

应用

Our Abpromise guarantee covers the use of ab113966 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.
  • 组织特异性
    Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts. Not expressed in proximal tubules or glomeruli.
  • 序列相似性
    Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acid sensitive potassium channel protein TASK 2 antibody
    • Acid-sensitive potassium channel protein TASK-2 antibody
    • FLJ11035 antibody
    • K2p5.1 antibody
    • KCNK 5 antibody
    • KCNK5 antibody
    • KCNK5_HUMAN antibody
    • Potassium channel subfamily K member 1 antibody
    • Potassium channel subfamily K member 5 antibody
    • TASK 2 antibody
    • TASK2 antibody
    • TWIK related acid sensitive K(+) channel 2 antibody
    • TWIK related acid sensitive K+ channel 2 antibody
    • TWIK-related acid-sensitive K(+) channel 2 antibody
    see all

图片

  • Anti-KCNK5 antibody (ab113966) at 1 µg/ml + Mouse liver lysate at 10 µg

    Predicted band size : 56 kDa

实验方案

文献

This product has been referenced in:
  • Hughes S  et al. Expression and localisation of two-pore domain (K2P) background leak potassium ion channels in the mouse retina. Sci Rep 7:46085 (2017). IHC-Fr ; Mouse . Read more (PubMed: 28443635) »

See 1 Publication for this product

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