概述

  • 产品名称
  • 描述
    兔多克隆抗体to KCNK3
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Sheep, Cow, Dog
  • 免疫原

    A region within synthetic peptide: IPMIIPRDLS TSDTCVEQSH SSPGGGGRYS DTPSRRCLCS GAPRSAISSV, corresponding to C terminal amino acids 325-374 of Human KCNK3

  • 阳性对照
    • Jurkat cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab49433 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 43 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA: titre using peptide based assay: 1/1562500.

靶标

  • 功能
    pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.
  • 组织特异性
    Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.
  • 疾病相关
    Pulmonary hypertension, primary, 4
  • 序列相似性
    Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acid sensitive potassium channel protein TASK 1 antibody
    • Acid sensitive potassium channel protein TASK antibody
    • Acid-sensitive potassium channel protein TASK-1 antibody
    • Cardiac two pore background K(+) channel antibody
    • cTBAK 1 antibody
    • K2p3.1 antibody
    • KCNK3 antibody
    • KCNK3_HUMAN antibody
    • OAT1 antibody
    • Potassium channel subfamily K member 3 antibody
    • potassium channel, subfamily K, member 3 antibody
    • Potassium inwardly rectifying channel subfamily K member 3 antibody
    • PPH4 antibody
    • rTASK antibody
    • TASK 1 antibody
    • TASK antibody
    • TBAK1 antibody
    • TWIK related acid sensitive K+ channel antibody
    • TWIK-related acid-sensitive K(+) channel 1 antibody
    • Two P domain potassium channel antibody
    • Two pore K(+) channel KT3. antibody
    • Two pore K(+) channel KT3.1 antibody
    • Two pore potassium channel KT3.1 antibody
    see all

图片

  • Anti-KCNK3 antibody (ab49433) at 1.25 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 43 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)

实验方案

文献

ab49433 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab49433.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册