概述

  • 产品名称Anti-KCNK10抗体
    参阅全部 KCNK10 一抗
  • 描述
    兔多克隆抗体to KCNK10
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog
  • 免疫原

    A region within synthetic peptide: HGQGASEDNI INKFGSTSRL TKRKNKDLKK TLPEDVQKIY KTFRNYSLDE, corresponding to C terminal amino acids 434-483 of Human KCNK10

  • 阳性对照
    • Jurkat cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab48868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.4 µg/ml. Detects a band of approximately 56 kDa (predicted molecular weight: 59 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/312500.

靶标

  • 功能Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
  • 组织特异性Abundantly expressed in pancreas and kidney and to a lower level in brain, testis, colon, and small intestine. Isoform b is strongly expressed in kidney (primarily in the proximal tubule) and pancreas, whereas isoform c is abundantly expressed in brain.
  • 序列相似性Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2P domain potassium channel TREK2 antibody
    • K2p10.1 antibody
    • KCNK10 antibody
    • KCNKA_HUMAN antibody
    • Outward rectifying potassium channel protein TREK 2 antibody
    • Outward rectifying potassium channel protein TREK-2 antibody
    • Potassium channel subfamily K member 10 antibody
    • Potassium channel TREK 2 antibody
    • TREK 2 antibody
    • TREK 2 K antibody
    • TREK 2 K(+) channel subunit antibody
    • TREK-2 K(+) channel subunit antibody
    • TREK2 antibody
    • TWIK related K+ channel 2 antibody
    see all

Anti-KCNK10 antibody 图像

  • Anti-KCNK10 antibody (ab48868) at 1.4 µg/ml (in 5% skimmed milk/PBS) + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 59 kDa
    Observed band size : 56 kDa (why is the actual band size different from the predicted?)

Anti-KCNK10 antibody (ab48868)参考文献

ab48868 has not yet been referenced specifically in any publications.

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