Anti-KCNIP1抗体[S55-7] (ab99013)

概述

  • 产品名称Anti-KCNIP1抗体[S55-7]
    参阅全部 KCNIP1 一抗
  • 描述
    小鼠单克隆抗体[S55-7] to KCNIP1
  • 特异性Does not cross react with Rat KCNIP 2 and 3.
  • 经测试应用适用于: ICC/IF, IP, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Full length fusion protein, corresponding to amino acids 1 - 216 of Rat KCNIP1 (Q8R426).

  • 阳性对照
    • Rat brain tissue

性能

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应用

Our Abpromise guarantee covers the use of ab99013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 0.1 - 1 µg/ml. (perox) or 1/40 dilution (IF).
IP Use at an assay dependent concentration.
IHC-P Use a concentration of 0.1 - 1 µg/ml. (perox) or 1/40 dilution (IF).
IHC-Fr Use a concentration of 0.1 - 1 µg/ml. (perox) or 1/40 dilution (IF).

靶标

  • 功能Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.
  • 组织特异性Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus.
  • 序列相似性Belongs to the recoverin family.
    Contains 4 EF-hand domains.
  • 细胞定位Cell membrane. Cytoplasm. Cell projection, dendrite.
  • Information by UniProt
  • 数据库链接
  • 形式There are 3 isoforms produced by alternative splicing.
  • 别名
    • A type potassium channel modulatory protein 1 antibody
    • A-type potassium channel modulatory protein 1 antibody
    • KChIP1 antibody
    • KCIP1_HUMAN antibody
    • Kcnip1 antibody
    • Kv channel interacting protein 1 antibody
    • Kv channel-interacting protein 1 antibody
    • MGC9 antibody
    • MGC95 antibody
    • Potassium channel interacting protein 1 antibody
    • Potassium channel-interacting protein 1 antibody
    • VABP antibody
    • Vesicle APC binding protein antibody
    • Vesicle APC-binding protein antibody
    see all

Anti-KCNIP1 antibody [S55-7] 图像

  • Immunohistochemical detection of KCNIP1 in frozen sections of Mouse brain extract using ab99013.

Anti-KCNIP1 antibody [S55-7] (ab99013)参考文献

ab99013 has not yet been referenced specifically in any publications.

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