概述

  • 产品名称Anti-KCNIP1抗体
    参阅全部 KCNIP1 一抗
  • 描述
    兔多克隆抗体to KCNIP1
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from the N-terminal of Human KCNIP1.

  • 阳性对照
    • Human brain tissue; HeLa cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49.1% PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: without Mg2+ and Ca2+
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab111217 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111217 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

靶标

  • 功能Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.
  • 组织特异性Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus.
  • 序列相似性Belongs to the recoverin family.
    Contains 4 EF-hand domains.
  • 细胞定位Cell membrane. Cytoplasm. Cell projection, dendrite.
  • Information by UniProt
  • 数据库链接
  • 形式There are 3 isoforms produced by alternative splicing.
  • 别名
    • A type potassium channel modulatory protein 1 antibody
    • A-type potassium channel modulatory protein 1 antibody
    • KChIP1 antibody
    • KCIP1_HUMAN antibody
    • Kcnip1 antibody
    • Kv channel interacting protein 1 antibody
    • Kv channel-interacting protein 1 antibody
    • MGC9 antibody
    • MGC95 antibody
    • Potassium channel interacting protein 1 antibody
    • Potassium channel-interacting protein 1 antibody
    • VABP antibody
    • Vesicle APC binding protein antibody
    • Vesicle APC-binding protein antibody
    see all

Anti-KCNIP1 antibody 图像

  • ab111217 at 1/50 dilution staining KCNIP1 in paraffin-embedded Human Brain tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.
  • ab111217 at 1/100 dilution staining KCNIP1 in HeLa cells by Immunofluorescence. The image on the right is treated with the synthesized peptide.

Anti-KCNIP1 antibody (ab111217)参考文献

ab111217 has not yet been referenced specifically in any publications.

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