概述

  • 产品名称
    Anti-KCNH8抗体
  • 描述
    兔多克隆抗体to KCNH8
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cat, Dog, Human, Pig
  • 免疫原

    Synthetic peptide from a region within C terminal amino acids 960-1009: LVGSSPQRTE AHEQNPADSE HHSPNLDYSP HCQVIQEGHL FLRCISP, of Mouse KCNH8 (NP_001026981).

  • 阳性对照
    • Mouse heart lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Constituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab113944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 124 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly.
  • 组织特异性
    Primarily expressed in the nervous system.
  • 序列相似性
    Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv12.1/KCNH8 sub-subfamily.
    Contains 1 cyclic nucleotide-binding domain.
    Contains 1 PAC (PAS-associated C-terminal) domain.
    Contains 1 PAS (PER-ARNT-SIM) domain.
  • 结构域
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C130090D05Rik antibody
    • ELK antibody
    • ELK channel 3 antibody
    • ELK1 antibody
    • elk3 antibody
    • Ether-a-go-go-like potassium channel 1 antibody
    • Ether-a-go-go-like potassium channel 3 antibody
    • hElk1 antibody
    • Kcnh8 antibody
    • KCNH8_HUMAN antibody
    • Kv12.1 antibody
    • Potassium voltage gated channel, subfamily H (eag-related), member 8 antibody
    • Potassium voltage-gated channel subfamily H member 8 antibody
    • Potassium voltage-gated channel, subfamily H, member 8 antibody
    • Voltage-gated potassium channel subunit Kv12.1 antibody
    see all

Anti-KCNH8 antibody 图像

  • Anti-KCNH8 antibody (ab113944) at 1 µg/ml + Mouse heart lysate at 10 µg

    Predicted band size : 124 kDa

实验方案

Anti-KCNH8 antibody (ab113944)参考文献

ab113944 has not yet been referenced specifically in any publications.

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