概述

  • 产品名称
    Anti-KCNAB3抗体
  • 描述
    兔多克隆抗体to KCNAB3
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    A region within synthetic peptide: GRGTGMKYRN LGKSGLRVSC LGLGTWVTFG SQISDETAED VLTVAYEHGV, corresponding to N terminal amino acids 73-122 of Human KCNAB3

  • 阳性对照
    • Human kidney tissue, Jurkat cell lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab66625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.65 µg/ml. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

靶标

  • 功能
    Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5.
  • 组织特异性
    Brain specific. Most prominent expression in cerebellum. Weaker signals detected in cortex, occipital lobe, frontal lobe and temporal lobe. Not detected in spinal cord, heart, lung, liver, kidney, pancreas, placenta and skeletal muscle.
  • 序列相似性
    Belongs to the shaker potassium channel beta subunit family.
  • 结构域
    Alteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AKR6A9 antibody
    • K antibody
    • K(+) channel subunit beta-3 antibody
    • K+ channel beta 3 subunit antibody
    • KCAB3_HUMAN antibody
    • KCNA3.1B antibody
    • KCNA3B antibody
    • KCNAB 3 antibody
    • Kcnab3 antibody
    • KV BETA 3 antibody
    • KV BETA3 antibody
    • Kv-beta-3 antibody
    • MGC116886 antibody
    • Voltage gated potassium channel subunit beta 3 antibody
    • Voltage-gated potassium channel subunit beta-3 antibody
    see all

Anti-KCNAB3 antibody 图像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling KCNAB3 with ab66625 at 4-8µg/ml. Arrows indicate positively labelled epithelial cells of the renal tubules. Magnification: 400X.

  • Anti-KCNAB3 antibody (ab66625) at 0.65 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 44 kDa
    Observed band size : 44 kDa
    Additional bands at : 34 kDa. We are unsure as to the identity of these extra bands.

Anti-KCNAB3 antibody (ab66625)参考文献

ab66625 has not yet been referenced specifically in any publications.

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