Anti-KCNA3抗体(ab123670)

概述

• 产品名称
  Anti-KCNA3抗体
  参阅全部 KCNA3 一抗
• 描述
  兔多克隆抗体to KCNA3
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Human
  
• 免疫原

  Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 238-268 of Human KCNA3 (NP_002223.3).

• 阳性对照
  • A549 cell line lysates.

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
• 存储溶液
  Preservative: 0.09% Sodium azide
  Constituent: 99% PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 纯化说明
  ab123670 is purified through a protein A column, followed by peptide affinity purification.
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Signal Transduction
  • Metabolism
  • Plasma Membrane
  • Channels

  • Metabolism
  • Types of disease
  • Cancer

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 功能
  Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
• 序列相似性
  Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
• 结构域
  The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
  The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
• 细胞定位
  Membrane.

• Target information above from: UniProt accession P22001 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 3738 Human
  • Omim: 176263 Human
  • SwissProt: P22001 Human
  • Unigene: 169948 Human
• 别名
  • HGK 5 antibody
  • HGK5 antibody
  • HLK 3 antibody

  • HLK3 antibody
  • HPCN 3 antibody
  • HPCN3 antibody
  • HuKIII antibody
  • KCNA 3 antibody
  • Kcna3 antibody
  • KCNA3_HUMAN antibody
  • KV1.3 antibody
  • MK 3 antibody
  • MK3 antibody
  • OTTHUMP00000032397 antibody
  • PCN 3 antibody
  • PCN3 antibody
  • Potassium channel 3 antibody
  • Potassium voltage gated channel shaker related subfamily member 3 antibody
  • Potassium voltage gated channel subfamily A member 3 antibody
  • Potassium voltage-gated channel subfamily A member 3 antibody
  • Type n potassium channel antibody
  • Voltage gated potassium channel protein Kv1.3 antibody
  • Voltage gated potassium channel subunit Kv1.3 antibody
  • Voltage-gated K(+) channel HuKIII antibody
  • Voltage-gated potassium channel subunit Kv1.3 antibody

  see all

实验方案

• Western blot protocols