概述

  • 产品名称Anti-Kazrin抗体
    参阅全部 Kazrin 一抗
  • 描述
    小鼠多克隆抗体to Kazrin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-415 of Human Kazrin (NP_001018000.1)

  • 阳性对照
    • Rat brain tissue lysate and transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab88752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 86 kDa.

靶标

  • 功能Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
  • 组织特异性Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).
  • 序列相似性Belongs to the kazrin family.
    Contains 3 SAM (sterile alpha motif) domains.
  • 细胞定位Cytoplasm > cytoskeleton and Cytoplasm. Cell junction > desmosome. Nucleus. Observed at the apical plasma mebrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HRIHFB2003 antibody
    • KAZ antibody
    • Kazn antibody
    • Kazrin antibody
    • KAZRN_HUMAN antibody
    • KIAA1026 antibody
    • RP1-21O18.1 antibody
    see all

Anti-Kazrin antibody 图像

  • Anti-Kazrin antibody (ab88752) at 1 µg/ml + Rat brain tissue lysate at 50ug/lane

    Predicted band size : 86 kDa
    Observed band size : 86 kDa
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-Kazrin antibody (ab88752) at 1 µg/ml

    Lane 1 : Kazrin transfected 293T cell lysate (45.65 kDa) at 25ug/lane
    Lane 2 : Non-transfected 293T cell lysate at 25ug/lane


    Predicted band size : 86 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

Anti-Kazrin antibody (ab88752)参考文献

ab88752 has not yet been referenced specifically in any publications.

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