Anti-katanin p80抗体(ab118219)

概述

  • 产品名称
    Anti-katanin p80抗体
    参阅全部 Katanin p80 一抗
  • 描述
    兔多克隆抗体to katanin p80
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant fragment, corresponding to amino acids 429-578 of Human katanin p80 (BC001353).

  • 阳性对照
    • Human fetal stomach tissue; Human fetal heart and fetal brain lysates.

性能

  • 形式
    Lyophilised:Add 200ul sterile distilled water.
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 1% BSA, 98% PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab118219 is purified by a protein affinity column.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab118219 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/2000. Detects a band of approximately 72 kDa (predicted molecular weight: 72 kDa).
IHC-P 1/100 - 1/500.

靶标

  • 功能
    Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
  • 序列相似性
    Belongs to the WD repeat KATNB1 family.
    Contains 6 WD repeats.
  • 细胞定位
    Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton. Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KAT antibody
    • Katanin (80 kDa) antibody
    • Katanin p80 (WD repeat containing) subunit B 1 antibody
    • Katanin p80 subunit B 1 antibody
    • Katanin p80 subunit B1 antibody
    • Katanin p80 WD40-containing subunit B1 antibody
    • katnb1 antibody
    • KTNB1_HUMAN antibody
    • OTTHUMP00000164672 antibody
    • p80 katanin antibody
    see all

图片

  • All lanes : Anti-katanin p80 antibody (ab118219) at 1/1000 dilution

    Lane 1 : Human fetal brain lysate
    Lane 2 : Human fetal heart lysate


    Predicted band size : 72 kDa
  • ab118219 at 1/100 dilution staining katanin p80 in Formalin-fixed, Paraffin-embedded Human fetal stomach tissue by Immunohistochemistry. Note cytoplasmic staining.

文献

ab118219 has not yet been referenced specifically in any publications.

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