Anti-KAT2B / PCAF抗体(ab56535)

概述

  • 产品名称Anti-KAT2B / PCAF抗体
    参阅全部 KAT2B / PCAF 一抗
  • 描述
    小鼠单克隆抗体to KAT2B / PCAF
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: LEEEVYSQNS PIWDQDFLSA SSRTSQLGIQ TVINPPPVAG TISYNSTSSS LEQPNAGSSS PACKASSGLE ANPGEKRKMT DSHVLEEAKK PRVMGDIPME , corresponding to amino acids 353-452 of Human PCAF

性能

应用

Our Abpromise guarantee covers the use of ab56535 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
    • 组织特异性Ubiquitously expressed but most abundant in heart and skeletal muscle.
    • 序列相似性Belongs to the GCN5 family.
      Contains 1 bromo domain.
      Contains 1 N-acetyltransferase domain.
    • 结构域The bromodomain mediates binding to HIV-1 Tat.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CAF antibody
      • CREBBP associated factor antibody
      • GCN5 antibody
      • GCN5L antibody
      • GCN5L1 antibody
      • Histone acetylase PCAF antibody
      • Histone acetyltransferase KAT2B antibody
      • Histone acetyltransferase PCAF antibody
      • K(lysine) acetyltransferase 2B antibody
      • KAT2B antibody
      • KAT2B_HUMAN antibody
      • Lysine acetyltransferase 2B antibody
      • P antibody
      • P/CAF antibody
      • p300/CBP associated factor antibody
      • P300/CBP-associated factor antibody
      • Pcaf antibody
      see all

    Anti-KAT2B / PCAF antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab56535 PCAF antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-KAT2B / PCAF antibody (ab56535)参考文献

    ab56535 has not yet been referenced specifically in any publications.

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