Anti-Kappa light chain抗体[L1C1] (FITC) (ab1185)


  • 产品名称Anti-Kappa light chain抗体[L1C1] (FITC)
    参阅全部 Kappa light chain 一抗
  • 描述
    小鼠单克隆抗体[L1C1] to Kappa light chain (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性This antibody reacts with kappa light chains of human immunoglobulins.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 常规说明

    This antigen is present in serum on all immunoglobulins bearing kappa light chains. It is also present on approximately 50% of normal human B lymphocytes.

    Measurement of kappa light chain in human lysed whole peripheral blood or mononuclear cells separated by density gradient. Studies of clonality of B cell lymphomas in tissue. Studies of clonality of B cell leukemias in peripheral blood. Kappa (FITC) immunofluorescence analysis can be performed on a flow cytometerequipped with an excitation source of 488nm and fitted with logarithmic amplifiers. 10µl of Kappa (FITC) is sufficient for labelling of 1x106 cells.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液PBS with 0.5% BSA and 0.1% sodium azide
  • Concentration information loading...
  • Primary antibody说明This antigen is present in serum on all immunoglobulins bearing kappa light chains. It is also present on approximately 50% of normal human B lymphocytes.
  • 克隆单克隆
  • 克隆编号L1C1
  • 骨髓瘤unknown
  • 同种型IgG1
  • 轻链类型unknown
  • 研究领域


Our Abpromise guarantee covers the use of ab1185 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration.


  • 相关性Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
  • 细胞定位Cytoplasmic and Secreted
  • 数据库链接
  • 别名
    • HCAK 1 antibody
    • HCAK1 antibody
    • Ig kappa chain C region antibody
    • IGKC antibody
    • IGKCD antibody
    • Immunoglobulin InV antibody
    • Immunoglobulin kappa constant antibody
    • Immunoglobulin kappa constant region antibody
    • Immunoglobulin kappa light chain antibody
    • Immunoglobulin kappa light chain constant region antibody
    • Immunoglobulin KM antibody
    • Kappa 1 immunoglobulin light chain antibody
    • kappa light chain antibody
    • Km antibody
    • MGC111575 antibody
    • MGC62011 antibody
    • MGC72072 antibody
    • MGC88770 antibody
    • MGC88771 antibody
    • MGC88809 antibody
    see all

Anti-Kappa light chain antibody [L1C1] (FITC) (ab1185)参考文献

ab1185 has not yet been referenced specifically in any publications.

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For product ab1185 we send 500uL, and for product ab91346 the volume is 2ml.

There aren’t significant differences between antibodies. Both are quite similar, but because of business related issues,...

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Thank you for your enquiry. I am sorry to hear that you have been having difficulties with this antibody. Quality is important to Abcam. The specificity you have been observing is alarming. I have raised this issue with our in house lab team for fu...

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