Anti-Kappa + CD19抗体[GA160 + CB19] (Dual color: FITC + PE) (ab1241)

概述

  • 产品名称
    Anti-Kappa + CD19抗体[GA160 + CB19] (Dual color: FITC + PE)
  • 描述
    小鼠单克隆抗体[GA160 + CB19] to Kappa + CD19 (Dual color: FITC + PE)
  • 偶联物
    Dual color: FITC + PE
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 常规说明

    This product is a mixture of two clones: Kappa = Clone:L1C1, Isotype:IgG1, Label:FITC CD19 = Clone:CB19, Isotype:IgG1, Label:PE

    The Kappa antigen is present in serum on all immunoglobulins bearing kappa light chains. It is also present on approximately 50% of normal human B lymphocytes. CD19: This antigen (MW = 95kDa) is present on 10-15% of human peripheral blood lymphocytes and approximately 60% of splenic lymphocytes. It is not expressed on T lymphocytes, granulocytes, activated T cells or monocytes. Moreover, CD19 is present on principal acute and chronic B cell leukemias and lymphomas.

    Studies of clonality of B cell leukemias in human lysed whole peripheral blood or mononuclear cells separated by density gradient. Studies of clonality of B cell lymphomas in tissue. Kappa (FITC) / CD19 (PE) immunofluorescence analysis can be performed on a flow cytometer equipped with an excitation source of 488nm and fitted with logarithmic amplifiers. 10µl ofKappa (FITC) / CD19 (PE) is sufficient for labelling 1x10<6 cells.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C.
  • 存储溶液
    PBS with 0.5% BSA and 0.1% sodium azide
  • Concentration information loading...
  • Primary antibody说明
    The Kappa antigen is present in serum on all immunoglobulins bearing kappa light chains. It is also present on approximately 50% of normal human B lymphocytes. CD19: This antigen (MW = 95kDa) is present on 10-15% of human peripheral blood lymphocytes and approximately 60% of splenic lymphocytes. It is not expressed on T lymphocytes, granulocytes, activated T cells or monocytes. Moreover, CD19 is present on principal acute and chronic B cell leukemias and lymphomas.
  • 克隆
    单克隆
  • 克隆编号
    GA160 + CB19
  • 骨髓瘤
    unknown
  • 轻链类型
    unknown
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab1241 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration.

靶标

  • 相关性
    CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It is expressed on approximately 10% of normal human peripheral blood cells and approximately 60% of splenic lymphocytes. It is not expressed on granulocytes, monocytes or T cells as defined by CD3 expression. Kappa is an antigen present in the serum of all immunoglobulins bearing kappa light chains. It is also present on 50-70% of normal human B-cells. cd19 antigen is a member of the immunoglobulin superfamily and has two Ig like domains. It is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. It is expressed on the majority of B-cell lineage malignancies, including most acute lymphoblastic leukaemias.
  • 细胞定位
    Cell Membrane and Cytoplasmic
  • 数据库链接
  • 别名
    • B lymphocyte antigen CD19 antibody
    • CD19 molecule antibody
    • CD19 antigen antibody
    • Differentiation antigen CD19 antibody
    • Ig kappa chain V-I region HK101 antibody
    • IGKC antibody
    • Immunoglobulin kappa constant antibody
    • immunoglobulin kappa light chain antibody
    see all

文献

ab1241 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab1241.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册