Anti-Kallikrein 8抗体(ab72800)


  • 产品名称Anti-Kallikrein 8抗体
    参阅全部 Kallikrein 8 一抗
  • 描述
    兔多克隆抗体to Kallikrein 8
  • 特异性Detects endogenous levels of fragment of activated Kallikrein 8 resulting from cleavage adjacent to Val33.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from human Kallikrein 8

  • 阳性对照
    • Extracts from Jurkat cells, treated with etoposide (25uM, 24hours)



Our Abpromise guarantee covers the use of ab72800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 28 kDa.
ELISA 1/10000.


  • 功能Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
  • 组织特异性Isoform 1 is predominantly expressed in the pancreas. Isoform 2 is expressed in adult brain and hippocampus. Isoform 1 and isoform 2 are found in fetal brain and placenta. Detected in salivary gland, uterus, thymus, breast, testis and kidney but not in spleen, liver, lung or normal ovarian tissue. Displays an 11.5-fold increase in Alzheimer disease hippocampus compared to controls and is overexpressed in some ovarian carcinomas. Expressed at low levels in normal skin while high levels are found in psoriasis vulgaris, seborrheic keratosis, lichen planus and squamous cell carcinoma skin samples. Expressed in the keratinocytes.
  • 序列相似性Belongs to the peptidase S1 family. Kallikrein subfamily.
    Contains 1 peptidase S1 domain.
  • 细胞定位Secreted. Cytoplasm. Shows a cytoplasmic distribution in the keratinocytes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Brain serine protease 1 antibody
    • BSP1 antibody
    • hK8 antibody
    • HNP antibody
    • HPN antibody
    • Kallikrein 8 (neuropsin/ovasin) antibody
    • Kallikrein related peptidase 8 antibody
    • Kallikrein-8 antibody
    • Kallikrein8 antibody
    • KLK 8 antibody
    • Klk8 antibody
    • KLK8 protein type 1 antibody
    • KLK8 protein type 2 antibody
    • KLK8_HUMAN antibody
    • Neuropsin antibody
    • neuropsin type 1 antibody
    • Neuropsin type 1, included antibody
    • Neuropsin type 2 antibody
    • Neuropsin type 2, included antibody
    • Neuropsin, mouse, homolog of antibody
    • NP antibody
    • NRPN antibody
    • Ovasin antibody
    • PRO322 antibody
    • Protease serine 19 antibody
    • PRSS 19 antibody
    • PRSS19 antibody
    • Serine protease 19 antibody
    • Serine protease kallikrein antibody
    • Serine protease kallikrein/ovasin/neuropsin antibody
    • Serine protease TADG 14 antibody
    • Serine protease TADG-14 antibody
    • Serine protease TADG14 antibody
    • TADG 14 antibody
    • TADG14 antibody
    • Tumor associated differentially expressed gene 14 antibody
    • Tumor associated differentially expressed gene 14 protein antibody
    • Tumor-associated differentially expressed gene 14 protein antibody
    • UNQ283 antibody
    see all

Anti-Kallikrein 8 antibody 图像

  • All lanes : Anti-Kallikrein 8 antibody (ab72800) at 1/1000 dilution

    Lane 1 : Jurkat cells extract
    Lane 2 : Jurkat cells extract with Cleaved peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 28 kDa
    Observed band size : 28 kDa
    Additional bands at : 24 kDa (possible cleavage fragment).

Anti-Kallikrein 8 antibody (ab72800)参考文献

ab72800 has not yet been referenced specifically in any publications.

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