Anti-Kallikrein 7抗体(ab96710)

概述

  • 产品名称Anti-Kallikrein 7抗体
    参阅全部 Kallikrein 7 一抗
  • 描述
    兔多克隆抗体to Kallikrein 7
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment corresponding to a region within amino acids 1-237 of Human Kallikrein 7

  • 阳性对照
    • Transfected 293T whole cell lysate, Cal27 tissue

性能

应用

Our Abpromise guarantee covers the use of ab96710 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 28 kDa.
IHC-P 1/100.

靶标

  • 功能May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-
    -Cys-7', '16-Tyr-
    -Leu-17', '25-Phe-
    -Tyr-26' and '26-Tyr-
    -Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
  • 组织特异性Abundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Also expressed in the brain, mammary gland, cerebellum, spinal cord and kidney. Lower levels in salivary glands, uterus, thymus, thyroid, placenta, trachea and testis. Up-regulated in ovarian carcinoma, especially late-stage serous carcinoma, compared with normal ovaries and benign adenomas (at protein level).
  • 序列相似性Belongs to the peptidase S1 family. Kallikrein subfamily.
    Contains 1 peptidase S1 domain.
  • 细胞定位Secreted. In ovarian carcinoma, secreted and also observed at the apical membrane and in cytoplasm at the invasive front.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Chymotryptic stratum corneum antibody
    • hK 7 antibody
    • hK7 antibody
    • hSCCE antibody
    • Kallikrein 7 (chymotryptic stratum corneum) antibody
    • Kallikrein related peptidase 7 antibody
    • Kallikrein-7 antibody
    • Kallikrein7 antibody
    • KLK 7 antibody
    • Klk7 antibody
    • KLK7_HUMAN antibody
    • Protease serine 6 antibody
    • PRSS 6 antibody
    • PRSS6 antibody
    • SCCE antibody
    • Serine protease 6 antibody
    • Signal protein antibody
    • Stratum corneum chymotryptic enzyme antibody
    see all

Anti-Kallikrein 7 antibody 图像

  • All lanes : Anti-Kallikrein 7 antibody (ab96710) at 1/500 dilution

    Lane 1 : Non-transfected 293T lysate
    Lane 2 : Kallikrein 7 transfected 293T lysate


    Predicted band size : 28 kDa
  • Immunohistochemical analysis of paraffin-embedded Cal27 using ab96710 at 1/100 dilution.

Anti-Kallikrein 7 antibody (ab96710)参考文献

ab96710 has not yet been referenced specifically in any publications.

Product Wall

L’immunogène d’ab7283 correspond aux acides amines 280-293 de la protéine kallikrein 5 humaine. Ces acides aminés sont présents chez la forme active de la protéine.

L’immunogène d&rsq...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"