RabMAb

Anti-Kaiso抗体[EPR4668] (ab124777)

概述

  • 产品名称Anti-Kaiso抗体[EPR4668]
    参阅全部 Kaiso 一抗
  • 描述
    兔单克隆抗体[EPR4668] to Kaiso
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Kaiso (Human)

  • 阳性对照
    • WB: Human heart, MCF7, C6, PC12 or NIH 3T3 lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab124777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 95 kDa (predicted molecular weight: 74 kDa).
  • 应用说明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2.
    • 组织特异性Expressed in vascular endothelium.
    • 序列相似性Contains 1 BTB (POZ) domain.
      Contains 3 C2H2-type zinc fingers.
    • 细胞定位Nucleus. Cytoplasm. Also cytoplasmic in cells grown at high densities.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Kaiso antibody
      • Kaiso protein antibody
      • Kaiso transcription factor antibody
      • KAISO_HUMAN antibody
      • Transcriptional regulator Kaiso antibody
      • ZBTB 33 antibody
      • Zbtb33 antibody
      • Zinc finger and BTB domain containing 33 antibody
      • Zinc finger and BTB domain-containing protein 33 antibody
      • Zinc finger transcription factor Kaiso antibody
      • ZNF 348 antibody
      • ZNF Kaiso antibody
      • ZNF348 antibody
      see all

    Anti-Kaiso antibody [EPR4668] 图像

    • All lanes : Anti-Kaiso antibody [EPR4668] (ab124777) at 1/1000 dilution

      Lane 1 : Human heart lysate
      Lane 2 : MCF7 lysate
      Lane 3 : C6 lysate
      Lane 4 : PC12 lysate
      Lane 5 : NIH 3T3 lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled Goat anti Rabbit IgG at 1/2000 dilution

      Predicted band size : 74 kDa
      Observed band size : 95 kDa (why is the actual band size different from the predicted?)

    Anti-Kaiso antibody [EPR4668] (ab124777)参考文献

    ab124777 has not yet been referenced specifically in any publications.

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