概述

  • 产品名称Anti-K0776抗体
    参阅全部 K0776 一抗
  • 描述
    兔多克隆抗体to K0776
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, from a region within C-terminal amino acids 433-463 of Human K0776 (O94874)

  • 阳性对照
    • MCF7 cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab103047 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 90 kDa.

靶标

  • 功能E3 UFM1-protein ligase that mediates ufmylation of target proteins such as DDRGK1/C20orf116. The function of ufmylation is unknown. May act as a tumor suppressor by inhibiting cell invasion, blocking NF-kappa-B signaling and increasing stability of CDK5RAP3.
  • 组织特异性Ubiquitously expressed, with a high expression in liver (at protein level). Low expression in several invasive hepatocellular carcinomas, such HepG2, Hep3B, HLE and PLC.
  • 序列相似性Belongs to the UFL1 family.
  • 翻译后修饰Ubiquitinated, leading to its degradation by the proteasome. Interaction with CDK5RAP3 protects each other against ubiquitination and degradation via the proteasome.
  • 细胞定位Endoplasmic reticulum. Cytoplasm. In cytoplasm colocalizes with CDK5RAP3.
  • Information by UniProt
  • 数据库链接
  • 别名
    • E3 UFM1-protein ligase 1 antibody
    • KIAA0776 antibody
    • LZAP-binding protein antibody
    • Maxer antibody
    • NLBP antibody
    • RCAD antibody
    • UFL1 antibody
    • UFL1_HUMAN antibody
    see all

Anti-K0776 antibody 图像

  • Anti-K0776 antibody (ab103047) at 1/100 dilution + MCF7 cell lysate at 35 µg

    Predicted band size : 90 kDa

Anti-K0776 antibody (ab103047)参考文献

ab103047 has not yet been referenced specifically in any publications.

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