Anti-Junctional Adhesion Molecule 1抗体[M.Ab.F11] (ab17261)


  • 产品名称Anti-Junctional Adhesion Molecule 1抗体[M.Ab.F11]
    参阅全部 Junctional Adhesion Molecule 1 一抗
  • 描述
    小鼠单克隆抗体[M.Ab.F11] to Junctional Adhesion Molecule 1
  • 特异性The antibody directly stimulates the aggregation and granule secretion of human platelets.
  • 经测试应用适用于: Flow Cyt, WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Unfortunately, this information is considered to be commercially sensitive



Our Abpromise guarantee covers the use of ab17261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
WB Use at an assay dependent concentration. Predicted molecular weight: 33 kDa.
IP Use at an assay dependent concentration.


  • 功能Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
  • 序列相似性Belongs to the immunoglobulin superfamily.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • 翻译后修饰N-glycosylated.
  • 细胞定位Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD 321 antibody
    • CD321 antibody
    • CD321 antigen antibody
    • ESTM33 antibody
    • F11 receptor antibody
    • F11R antibody
    • JAM 1 antibody
    • JAM A antibody
    • JAM antibody
    • JAM-1 antibody
    • JAM-A antibody
    • JAM1 antibody
    • JAM1_HUMAN antibody
    • JAMA antibody
    • JCAM antibody
    • Jcam1 antibody
    • Junction adhesion molecule 1 antibody
    • Junction adhesion molecule, mouse, homolog of antibody
    • Junctional adhesion molecule 1 antibody
    • Junctional adhesion molecule A antibody
    • KAT antibody
    • Ly106 antibody
    • PAM 1 antibody
    • PAM-1 antibody
    • PAM1 antibody
    • Platelet adhesion molecule 1 antibody
    • Platelet adhesion molecule antibody
    • Platelet F11 receptor antibody
    • PRO301 antibody
    • UNQ264 antibody
    see all

Anti-Junctional Adhesion Molecule 1 antibody [M.Ab.F11] (ab17261)参考文献

This product has been referenced in:
  • Dautzenberg IJ  et al. Mammalian orthoreovirus T3D infects U-118 MG cell spheroids independent of junction adhesion molecule-A. Gene Ther 21:609-17 (2014). Human . Read more (PubMed: 24739522) »
  • van den Hengel SK  et al. Heterogeneous reovirus susceptibility in human glioblastoma stem-like cell cultures. Cancer Gene Ther 20:507-13 (2013). Read more (PubMed: 23907517) »

See all 4 Publications for this product

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