Anti-Junctional Adhesion Molecule 1/JAM-A抗体(ab91501)
Key features and details
- Goat polyclonal to Junctional Adhesion Molecule 1/JAM-A
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-Junctional Adhesion Molecule 1/JAM-A抗体
参阅全部 Junctional Adhesion Molecule 1/JAM-A 一抗 -
描述
山羊多克隆抗体to Junctional Adhesion Molecule 1/JAM-A -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cat, Dog, Pig -
免疫原
Synthetic peptide corresponding to Human Junctional Adhesion Molecule 1/JAM-A aa 282-295 (C terminal).
Sequence:C-QPSARSEGEFKQTS
Database link: NP_058642.1 -
阳性对照
- Human peripheral bood mononucleocyte lysate
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris buffered saline, 0.5% BSA -
Concentration information loading...
-
纯度
Immunogen affinity purified -
纯化说明
ab91501 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab91501于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
Use a concentration of 0.3 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 33 kDa).
A 1 hour primary incubation is recommended for this product. |
说明 |
---|
WB
Use a concentration of 0.3 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 33 kDa). A 1 hour primary incubation is recommended for this product. |
靶标
-
功能
Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. -
序列相似性
Belongs to the immunoglobulin superfamily.
Contains 2 Ig-like V-type (immunoglobulin-like) domains. -
翻译后修饰
N-glycosylated. -
细胞定位
Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells. - Information by UniProt
-
数据库链接
- Entrez Gene: 50848 Human
- Entrez Gene: 16456 Mouse
- Entrez Gene: 116479 Rat
- Omim: 605721 Human
- SwissProt: Q9Y624 Human
- SwissProt: O88792 Mouse
- SwissProt: Q9JHY1 Rat
- Unigene: 517293 Human
see all -
别名
- CD 321 antibody
- CD321 antibody
- CD321 antigen antibody
see all
图片
-
Anti-Junctional Adhesion Molecule 1/JAM-A antibody (ab91501) at 0.3 µg/ml + Human Peripheral Blood Mononucleocyte lysate at 35 µg
Predicted band size: 33 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted?
The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources.
数据表及文件
-
Datasheet download
文献 (0)
ab91501 尚未被引用在任何文献中。