概述

  • 产品名称Anti-JTB抗体
    参阅全部 JTB 一抗
  • 描述
    小鼠单克隆抗体to JTB
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-147 of Human JTB

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
    • 组织特异性Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.
    • 序列相似性Belongs to the JTB family.
    • 细胞定位Membrane. Mitochondrion. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
    • Information by UniProt
    • 数据库链接
    • 别名
      • hJT antibody
      • HJTB antibody
      • HSPC222 antibody
      • JTB antibody
      • JTB_HUMAN antibody
      • Jumping translocation breakpoint antibody
      • Jumping translocation breakpoint protein antibody
      • OTTHUMP00000034759 antibody
      • PAR antibody
      • PAR protein antibody
      • Prostate androgen regulated protein antibody
      • Prostate androgen-regulated protein antibody
      • Protein JTB antibody
      see all

    Anti-JTB antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab56798 JTB antibody at 1ug/ml. Predicted band size of immunogen is 42 kDa

    Anti-JTB antibody (ab56798)参考文献

    ab56798 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"