Anti-JMJD7-PLA2G4B抗体(ab118127)

概述

  • 产品名称Anti-JMJD7-PLA2G4B抗体
  • 描述
    兔多克隆抗体to JMJD7-PLA2G4B
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-316 of Human JMJD7-PLA2G4B (ENSP00000334326).

  • 阳性对照
    • JMJD7-PLA2G4B transfected 293T cell line.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituent: 99% Whole serum
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab118127 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 35.9 kDa.
IP Use at an assay dependent dilution.

靶标

  • 功能Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position with a preference for arachidonoyl phospholipids. Has a much weaker activity than PLA2G4A. Isoform 3 has calcium-dependent activity against palmitoyl-arachidonyl-phosphatidylethanolamine and low level lysophospholipase activity but no activity against phosphatidylcholine.
  • 组织特异性Widely expressed. Expressed at higher level in brain, heart, liver, cerebellum and pancreas. Isoform 3 is widely expressed.
  • 序列相似性Contains 1 C2 domain.
    Contains 1 PLA2c domain.
  • 结构域The N-terminal C2 domain associates with lipid membranes upon calcium binding. It modulates enzyme activity by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+).
  • 细胞定位Cytoplasm > cytosol and Mitochondrion membrane. Early endosome membrane. Translocates to membrane vesicles in a calcium-dependent fashion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • cPLA2-beta antibody
    • Cytosolic phospholipase A2 beta antibody
    • HsT16992 antibody
    • JMJD7-PLA2G4B protein antibody
    • Jumonji domain containing 7 phospholipase A2, group IVB (cytosolic) read-through antibody
    • OTTHUMP00000041703 antibody
    • OTTHUMP00000201605 antibody
    • PA24B_HUMAN antibody
    • Phospholipase A2 group IVB antibody
    • PHOSPHOLIPASE A2, CYTOSOLIC, CALCIUM-DEPENDENT, BETA antibody
    • PLA2G4B antibody
    see all

Anti-JMJD7-PLA2G4B antibody 图像

  • All lanes : Anti-JMJD7-PLA2G4B antibody (ab118127) at 1/1000 dilution

    Lane 1 : 293T cell line lysate, transfected with JMJD7-PLA2G4B
    Lane 2 : 293T cell line lysate, non-transfected

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 35.9 kDa
  • Immunoprecipitation of JMJD7-PLA2G4B transfected lysate using ab118127 and Protein A Magnetic Bead, and immunoblotted with JMJD7-PLA2G4B mouse polyclonal antibody.

Anti-JMJD7-PLA2G4B antibody (ab118127)参考文献

ab118127 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab118127.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"