概述

  • 产品名称Anti-JMJD1C抗体
    参阅全部 JMJD1C 一抗
  • 描述
    兔多克隆抗体to JMJD1C
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cow, Chimpanzee, Ferret, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 150 and 200 of Human JMJD1C (NP_004232.2)

  • 阳性对照
    • Human laryngeal squamous cell carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab84544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes.
    • 序列相似性Belongs to the JHDM2 histone demethylase family.
      Contains 1 JmjC domain.
    • 结构域Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • JHD2C_HUMAN antibody
      • Jmjd1c antibody
      • Jumonji domain containing 1C antibody
      • Jumonji domain-containing protein 1C antibody
      • Probable JmjC domain-containing histone demethylation protein 2C antibody
      • Thryoid receptor interacting protein antibody
      • Thyroid receptor-interacting protein 8 antibody
      • TR-interacting protein 8 antibody
      • TRIP-8 antibody
      • TRIP8 antibody
      see all

    Anti-JMJD1C antibody 图像

    • ab84544 at 1/100 dilution staining JMJD1C in Human laryngeal squamous cell carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    Anti-JMJD1C antibody (ab84544)参考文献

    ab84544 has not yet been referenced specifically in any publications.

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