概述

  • 产品名称
  • 描述
    兔多克隆抗体to JM4
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide: LLLEAL GQEQEAGS, corresponding to C terminal amino acids 165-178 of Human JM4

  • 阳性对照
    • Brain tissue (cortex).

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.05% Sodium Azide
    Constituents: 0.2% BSA, 10mM PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab40167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 功能
    May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.
  • 组织特异性
    Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non-neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.
  • 序列相似性
    Belongs to the PRA1 family.
  • 细胞定位
    Endosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Jena Muenchen 4 antibody
    • JM 4 antibody
    • PRA1 domain family member 2 antibody
    • PRA1 family protein 2 antibody
    • PRAF2 antibody
    • PRAF2_HUMAN antibody
    see all

Anti-JM4 antibody 图像

  • ab40167 at a 1:100 dilution staining JM4 in human brain tissue (cortex).

Anti-JM4 antibody (ab40167)参考文献

ab40167 has not yet been referenced specifically in any publications.

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