概述

  • 产品名称Anti-Jagged 2抗体[EPR3646]
    参阅全部 Jagged 2 一抗
  • 描述
    兔单克隆抗体[EPR3646] to Jagged 2
  • 经测试应用适用于: ICC/IF, WB, ICCmore details
    不适用于: Flow Cyt,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide corresponding to the extracellular domain of Human Jagged 2.

  • 阳性对照
    • HeLa, HUVEC and HT-29 cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab109627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration. PubMed: 24901044
WB 1/1000 - 1/10000. Predicted molecular weight: 133 kDa.
ICC 1/100 - 1/250.
  • 应用说明Is unsuitable for Flow Cyt,IHC-P or IP.
  • 靶标

    • 相关性Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
    • 细胞定位Cell Membrane
    • 数据库链接
    • 别名
      • D12Ggc2e antibody
      • HJ 2 antibody
      • HJ2 antibody
      • JAG 2 antibody
      • JAG2 antibody
      • Jagged 2 precursor antibody
      • Jagged2 antibody
      • Protein jagged 2 antibody
      • SER2 antibody
      • Syndactylism antibody
      see all

    Anti-Jagged 2 antibody [EPR3646] 图像

    • All lanes : Anti-Jagged 2 antibody [EPR3646] (ab109627) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HUVEC cell lysate
      Lane 3 : HT-29 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled Goat anti-Rabbit at 1/2000 dilution

      Predicted band size : 133 kDa

    Anti-Jagged 2 antibody [EPR3646] (ab109627)参考文献

    This product has been referenced in:
    • Zhou J  et al. Protective role of microRNA-29a in denatured dermis and skin fibroblast cells after thermal injury. Biol Open N/A:N/A (2016). WB ; Human . Read more (PubMed: 26794609) »
    • Zhang X  et al. FADD regulates thymocyte development at the ß-selection checkpoint by modulating Notch signaling. Cell Death Dis 5:e1273 (2014). ICC/IF ; Mouse . Read more (PubMed: 24901044) »

    See all 2 Publications for this product

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