概述

  • 产品名称
  • 描述
    兔多克隆抗体to IZUMO2
  • 特异性
    ab122776 is predicted to react with isoform 2 due to sequence homology.
  • 经测试应用
    适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: PSRFQLEQLQ ARAGAVLMGM EGPFFRDYAL NVFVGKVETN QLDLVASFVK NQTQHLMGNS LKDEPLLEEL VTLR, corresponding to internal sequence amino acids 41-114 of Human IZUMO2.

  • 阳性对照
    • Human kidney tissue.

性能

应用

Our Abpromise guarantee covers the use of ab122776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

靶标

  • 序列相似性
    Belongs to the Izumo family.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C19orf41 antibody
    • IZUM2_HUMAN antibody
    • Izumo sperm-egg fusion protein 2 antibody
    • Izumo2 antibody
    • MGC33947 antibody
    • PLAL6978 antibody
    • PRO21961 antibody
    • SCRL antibody
    • UNQ6978 antibody
    see all

Anti-IZUMO2 antibody 图像

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus and nucleoli. Recommended concentration of ab122776 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122776, at 1/1000 dilution, staining IZUMO2 in Paraffin Embedded Human kidney tissue by Immunohistochemistry.

Anti-IZUMO2 antibody (ab122776)参考文献

ab122776 has not yet been referenced specifically in any publications.

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