Anti-IVD抗体(ab95994)
Key features and details
- Rabbit polyclonal to IVD
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-IVD抗体
参阅全部 IVD 一抗 -
描述
兔多克隆抗体to IVD -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rat, Cow, Pig -
免疫原
Recombinant fragment containing a sequence corresponding to a region within amino acids 1-192 of Human IVD (AAH17202).
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阳性对照
- HeLa and Jurkat whole cell lysates
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab95994于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 46 kDa.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 46 kDa. |
靶标
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通路
Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 1/3. -
疾病相关
Defects in IVD are the cause of isovaleric acidemia (IVA) [MIM:243500]. IVA is characterized by retarded psychomotor development, a peculiar odor resembling sweaty feet, an aversion to dietary protein, and pernicious vomiting, leading to acidosis and coma. The acute neonatal form leads to massive metabolic acidosis from the first days of life and rapid death. -
序列相似性
Belongs to the acyl-CoA dehydrogenase family. -
细胞定位
Mitochondrion matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 510440 Cow
- Entrez Gene: 3712 Human
- Entrez Gene: 100156047 Pig
- Entrez Gene: 24513 Rat
- Omim: 607036 Human
- SwissProt: Q3SZI8 Cow
- SwissProt: P26440 Human
- SwissProt: P12007 Rat
see all -
别名
- ACAD2 antibody
- FLJ12715 antibody
- FLJ34849 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab95994 被引用在 1 文献中.
- Cappallo-Obermann H et al. Highly purified spermatozoal RNA obtained by a novel method indicates an unusual 28S/18S rRNA ratio and suggests impaired ribosome assembly. Mol Hum Reprod 17:669-78 (2011). PubMed: 21593214