概述

  • 产品名称Anti-ITPR3抗体
    参阅全部 ITPR3 一抗
  • 描述
    兔多克隆抗体to ITPR3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (Human) corresponding to a C terminal sequence.

性能

应用

Our Abpromise guarantee covers the use of ab55983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 304 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
  • 组织特异性Expressed in intestinal crypt and villus epithelial cells.
  • 序列相似性Belongs to the InsP3 receptor family.
    Contains 5 MIR domains.
  • 结构域The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.
  • 翻译后修饰Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4 antibody
    • 5-trisphosphate receptor antibody
    • 5-trisphosphate receptor type 3 antibody
    • FLJ36205 antibody
    • Inositol 1 antibody
    • Inositol 1,4,5 trisphosphate receptor type 3 antibody
    • InsP3R3 antibody
    • IP3 receptor antibody
    • IP3 receptor isoform 3 antibody
    • IP3R 3 antibody
    • IP3R antibody
    • IP3R3 antibody
    • ITPR 3 antibody
    • ITPR3 antibody
    • ITPR3_HUMAN antibody
    • Type 3 inositol 1 antibody
    • Type 3 inositol 1,4,5 trisphosphate receptor antibody
    • Type 3 InsP3 receptor antibody
    see all

Anti-ITPR3 antibody (ab55983)参考文献

ab55983 has not yet been referenced specifically in any publications.

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