概述

  • 产品名称Anti-ITPR3抗体
    参阅全部 ITPR3 一抗
  • 描述
    兔多克隆抗体to ITPR3
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Guinea pig, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region within amino acids 625-675 of Human ITPR3 (NP_002215.2).

  • 阳性对照
    • Human Breast Carcinoma, Colon Carcinoma, Osteosarcoma, Ovarian Carcinoma, and Stomach Adenocarcinoma tissues

性能

应用

Our Abpromise guarantee covers the use of ab113292 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

靶标

  • 功能Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
  • 组织特异性Expressed in intestinal crypt and villus epithelial cells.
  • 序列相似性Belongs to the InsP3 receptor family.
    Contains 5 MIR domains.
  • 结构域The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.
  • 翻译后修饰Phosphorylated on tyrosine residues. Phosphorylated by AKT1 on serine and/or threonine residues.
  • 细胞定位Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 4 antibody
    • 5-trisphosphate receptor antibody
    • 5-trisphosphate receptor type 3 antibody
    • FLJ36205 antibody
    • Inositol 1 antibody
    • Inositol 1,4,5 trisphosphate receptor type 3 antibody
    • InsP3R3 antibody
    • IP3 receptor antibody
    • IP3 receptor isoform 3 antibody
    • IP3R 3 antibody
    • IP3R antibody
    • IP3R3 antibody
    • ITPR 3 antibody
    • ITPR3 antibody
    • ITPR3_HUMAN antibody
    • Type 3 inositol 1 antibody
    • Type 3 inositol 1,4,5 trisphosphate receptor antibody
    • Type 3 InsP3 receptor antibody
    see all

Anti-ITPR3 antibody 图像

  • ab113292, at 1/250 dilution, staining ITPR3 in formalin-fixed, paraffin-embedded Human stomach carcinoma by Immunohistochemistry with DAB staining.
  • ab113292, at 1/250 dilution, staining ITPR3 in formalin-fixed, paraffin-embedded Human stomach carcinoma by Immunohistochemistry. Detection: Red-fluorescent Goat anti-Rabbit IgG-heavy and light chain cross-adsorbed Antibody DyLight® 594 Conjugated used at a dilution of 1/100.

Anti-ITPR3 antibody (ab113292)参考文献

ab113292 has not yet been referenced specifically in any publications.

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