概述

  • 产品名称Anti-ITPKA抗体
    参阅全部 ITPKA 一抗
  • 描述
    兔多克隆抗体to ITPKA
  • 特异性This antibody detects endogenous levels of total ITPKA protein.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    A synthetic peptide derived from C-terminal of human ITPKA

  • 阳性对照
    • Extracts from HUVEC cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab64811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).
ELISA 1/20000.

靶标

  • 相关性ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of ITPKA is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.
  • 细胞定位cytosol
  • 数据库链接
  • 别名
    • 1D myo inositol trisphosphate 3 kinase A antibody
    • EC 2.7.1.127 antibody
    • Inositol 1 4 5 trisphosphate 3 kinase A antibody
    • Inositol trisphosphate 3 kinase A antibody
    • IP3 3 kinase A antibody
    • IP3K A antibody
    • IP3KA antibody
    see all

Anti-ITPKA antibody 图像

  • All lanes : Anti-ITPKA antibody (ab64811) at 1/500 dilution

    Lane 1 : Extracts of HUVEC cells (5-30ug of total protiens)
    Lane 2 : Extracts of HUVEC cells (5-30ug of total protiens) with immunising peptide (5-10ug)


    Predicted band size : 51 kDa
    Observed band size : 51 kDa
    Additional bands at : 34 kDa. We are unsure as to the identity of these extra bands.

Anti-ITPKA antibody (ab64811)参考文献

ab64811 has not yet been referenced specifically in any publications.

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