概述

  • 产品名称Anti-ITGA11抗体
    参阅全部 ITGA11 一抗
  • 描述
    山羊多克隆抗体to ITGA11
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat
  • 免疫原

    Synthetic peptide:

    C-PTEEDLSHAPQRNH

    , corresponding to C terminal amino acids 1047-1060 of Mouse ITGA11 (NP_795896.4).

  • 阳性对照
    • Mouse skeletal muscle lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 99.48% Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab114113 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab114113 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 140 kDa (predicted molecular weight: 133 kDa).

靶标

  • 功能Integrin alpha-11/beta-1 is a receptor for collagen.
  • 组织特异性According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver.
  • 序列相似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • 发展阶段Strongly up-regulated in differentiating fetal muscle cells (in vitro).
  • 结构域The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • integrin a11 antibody
    • Integrin alpha 11 antibody
    • Integrin alpha-11 antibody
    • ITA11_HUMAN antibody
    • ITGA11 antibody
    see all

Anti-ITGA11 antibody 图像

  • Anti-ITGA11 antibody (ab114113) at 1 µg/ml + Mouse skeletal muscle lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 133 kDa
    Observed band size : 140 kDa (why is the actual band size different from the predicted?)

Anti-ITGA11 antibody (ab114113)参考文献

ab114113 has not yet been referenced specifically in any publications.

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