概述

  • 产品名称
  • 描述
    小鼠单克隆抗体to IRX5
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: PQKPEDKADP EGPEAGGAEQ KAASGCERLQ GPPTPAGKET EGSLSDSDFK EPPSEGRLDA L, corresponding to amino acids 204-265 of Human IRX5

  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

应用

Our Abpromise guarantee covers the use of ab56681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 50 kDa.

靶标

  • 功能
    Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells.
  • 序列相似性
    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Homeodomain protein IRX-2A antibody
    • Homeodomain protein IRXB2 antibody
    • Iroquois homeobox protein 5 antibody
    • Iroquois-class homeodomain protein IRX-5 antibody
    • IRX2A antibody
    • Irx5 antibody
    • IRX5_HUMAN antibody
    • IRXB2 antibody
    see all

Anti-IRX5 antibody 图像



  • Predicted band size : 50 kDa
    IRX5 antibody (ab56681) at 1ug/lane + HepG2 cell lysate at 25ug/lane.

实验方案

Anti-IRX5 antibody (ab56681)参考文献

This product has been referenced in:
  • Singh B  et al. Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge. PLoS One 11:e0159072 (2016). WB ; Human . Read more (PubMed: 27390851) »
  • Panguluri SK  et al. Hyperoxia-induced hypertrophy and ion channel remodeling in left ventricle. Am J Physiol Heart Circ Physiol 304:H1651-61 (2013). Mouse . Read more (PubMed: 23585127) »

See all 2 Publications for this product

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