概述

  • 产品名称Anti-IRX5抗体
    参阅全部 IRX5 一抗
  • 描述
    兔多克隆抗体to IRX5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Cow, Dog, Zebrafish, Macaque Monkey
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Human IRX5.

  • 阳性对照
    • This antibody gave a positive signal in the following human whole cell lysates: HEK293; HeLa; PC3; DU145.

性能

应用

Our Abpromise guarantee covers the use of ab100939 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/250. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).

靶标

  • 功能Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells.
  • 序列相似性Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Homeodomain protein IRX-2A antibody
    • Homeodomain protein IRXB2 antibody
    • Iroquois homeobox protein 5 antibody
    • Iroquois-class homeodomain protein IRX-5 antibody
    • IRX2A antibody
    • Irx5 antibody
    • IRX5_HUMAN antibody
    • IRXB2 antibody
    see all

Anti-IRX5 antibody 图像

  • All lanes : Anti-IRX5 antibody (ab100939) at 1/250 dilution

    Lane 1 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate
    Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate
    Lane 3 : PC3 (Human prostate carcinoma cell line) Whole Cell Lysate Whole Cell Lysate
    Lane 4 : DU 145 (Human prostate carcinoma cell line) Whole Cell Lysate

    Lysates/proteins at 20 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 50 kDa
    Observed band size : 50 kDa
    Additional bands at : 21 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

Anti-IRX5 antibody (ab100939)参考文献

ab100939 has not yet been referenced specifically in any publications.

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