Anti-IRX5抗体(ab100939)
Key features and details
- Rabbit polyclonal to IRX5
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-IRX5抗体
参阅全部 IRX5 一抗 -
描述
兔多克隆抗体to IRX5 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Horse, Cow, Dog, Zebrafish, Macaque monkey -
免疫原
Synthetic peptide corresponding to Human IRX5 aa 150-250 conjugated to keyhole limpet haemocyanin.
(Peptide available asab114000) -
阳性对照
- This antibody gave a positive signal in the following human whole cell lysates: HEK293; HeLa; PC3; DU145.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab100939于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/250. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).
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说明 |
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WB
1/250. Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa). |
靶标
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功能
Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. -
序列相似性
Belongs to the TALE/IRO homeobox family.
Contains 1 homeobox DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 10265 Human
- Entrez Gene: 54352 Mouse
- Entrez Gene: 498918 Rat
- Omim: 606195 Human
- SwissProt: A2RRB5 Human
- SwissProt: P78411 Human
- SwissProt: Q9JKQ4 Mouse
- Unigene: 435730 Human
see all -
别名
- Homeodomain protein IRX-2A antibody
- Homeodomain protein IRXB2 antibody
- Iroquois homeobox protein 5 antibody
see all
图片
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All lanes : Anti-IRX5 antibody (ab100939) at 1/250 dilution
Lane 1 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate
Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate
Lane 3 : PC3 (Human prostate carcinoma cell line) Whole Cell Lysate Whole Cell Lysate
Lane 4 : DU 145 (Human prostate carcinoma cell line) Whole Cell Lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 50 kDa
Observed band size: 50 kDa
Additional bands at: 21 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 20 minutes
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab100939 尚未被引用在任何文献中。